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Cursus: FA-BA314
FA-BA314
Future medicines
Cursus informatieRooster
CursuscodeFA-BA314
Studiepunten (ECTS)7,5
Categorie / Niveau3 (Bachelor Gevorderd)
CursustypeCursorisch onderwijs
VoertaalEngels
Aangeboden doorFaculteit Betawetenschappen; School of Pharmacy, fac. Betawetenschappen;
Contactpersoondr. E.E. Moret
Telefoon+316 20255134
E-maile.e.moret@uu.nl
Docenten
Contactpersoon van de cursus
dr. E.E. Moret
Overige cursussen docent
Blok
1  (02-09-2019 t/m 08-11-2019)
Aanvangsblok
1/  3
TimeslotBC: Zie 'Help'
Onderwijsvorm
Voltijd
Cursusinschrijving geopendvanaf 03-06-2019 t/m 30-06-2019
AanmeldingsprocedureOsiris
Inschrijven via OSIRISJa
Inschrijven voor bijvakkersJa
VoorinschrijvingNee
Na-inschrijvingJa
Na-inschrijving geopendvanaf 19-08-2019 t/m 20-08-2019
WachtlijstJa
PlaatsingsprocedureStudiepunt/Student desk
Cursusdoelen
After finishing successfully the student is able to:
  • Describe the various stages of drug development from preclinical to post-marketing and understand the roles of different stakeholders: patients, doctors, researchers and industry
  • Understand at a molecular and posttranslational level how humans differ and how disease differs from health and what the consequences are for innovative therapy or prevention
  • Understand personal variation in histocompatibility and in glycans
  • Explain what precision medicine means and what it will mean for the pharmaceutical industry and understand the method of diagnosis (including biomarkers) and companion diagnostics
  • Think of solutions for the barriers that currently face cell and gene therapy, as well as regenerative medicine
  • Assess the limits of “personalised” and of (bio)similarity
  • Discuss alternative business models, like drug repurposing
Inhoud
This course is an elective for life sciences students in year two or three of the bachelor programme.
The main trend is towards advanced therapy medicinal products (ATMP), which include biomolecules and cells, focusing on disease modification and on personal differences: personalised medicine. But a better understanding of a person’s characteristics or disease characteristics can also be exploited by repurposing of old medicines.
In this course we will study personalised medicine at several levels. Molecular, cellular, organ, organism, and population. The course starts with an individual assignment of a recent first in class medicine and ends with group assignments on future medicines.
•              Weeks one and two. The latest medicines and how they were developed.
•              Weeks three and four. Drug repurposing.
•              Weeks five and six. Cell and gene therapy and regenerative medicine. 
•              Weeks seven and eight. The self; our compatibility gene.
•              Weeks nine and ten. Glycomics and related diseases.
Competenties
-
Ingangseisen
-
Voorkennis
knowledge (bio)chemistry, cell biology, pharmacology, immunology
Verplicht materiaal
-
Werkvormen
Groepsonderwijs

Algemeen
Individual writing assignment

Bijdrage aan groepswerk
Group presentations

Hoorcollege

Toetsen
Eindresultaat
Weging100
Minimum cijfer5,5

Beoordeling
The grade is composed of the following assessments:
- Drug Monograph 40% (individual grade)
- Glycan disease presentation 20% (team grade)
- HLA presentation 10% (team grade)
- HLA report 10% (team grade)
- Gene and cell therapy case report solutions 20% (team grade)

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