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Course module: FA-450
FA-450
Chemical Biology
Course info
Course codeFA-450
ECTS Credits7.5
Category / LevelM (Master)
Course typeCourse
Language of instructionEnglish
Offered byFaculty of Science; School of Pharmacy, fac. Betawetenschappen;
Contact persondr. S.A.K. Jongkees
E-mails.a.k.jongkees@uu.nl
Lecturers
Contactperson for the course
dr. S.A.K. Jongkees
Other courses by this lecturer
Teaching period
3.2  (11/03/2019 to 19/04/2019)
Teaching period in which the course begins
3.2
Time slot-: Not in use
Study mode
Full-time
Enrolment periodfrom 29/10/2018 up to and including 25/11/2018
Course application processOsiris
Enrolling through OSIRISYes
Enrolment open to students taking subsidiary coursesYes
Pre-enrolmentNo
Post-registrationYes
Post-registration openfrom 21/01/2019 up to and including 22/01/2019
Waiting listNo
Course placement processStudiepunt/Student desk
Aims
 On completion of this course, the student will be able to:
 
  • Demonstrate an appreciation of the chemical nature of biological systems and the biological behaviour of chemicals.
  • Demonstrate an understanding of the chemical and biological synthesis of biomolecules (nucleic acids, peptides, and carbohydrates).
  • Demonstrate an understanding of the three dimensional structure of biomolecules, and how this structure interacts with function.
  • Demonstrate an understanding of recent developments in selection-based discovery methods, bio-orthogonal chemistry, and chemical probes of biological systems
  • Critically read research articles in the literature, and present this information in a manner accessible to peers.
Content
 The field of chemical biology lies at the interface of chemistry and biology. It uses chemistry, chemical principles, and notably molecules to study and solve important issues in biology. The course will focus on chemical and biological syntheses and behaviours of relevant molecules for chemical biology, primarily carbohydrates, peptides and nucleic acids, as well as their uses in addressing biological questions. Bio-orthogonal reactions and the use of the compounds derivatized as chemical probes will also be discussed. This course will also have an emphasis on critical reading of recent literature and presentation on this to the group.
 
Entry requirements
Prerequisite knowledge
Participants should have a solid foundation in organic chemistry and biochemistry. This course will assume reasonable knowledge of chemical functional groups, reactivity, and mechanisms. A second year chemistry course level is required, such as FA-CPS-311 or SK-BORC13 or equivalent, while aspects of a third year chemistry course would be beneficial, such as SK-BORC3 or equivalent. A first year biochemistry course is also recommended.
Required materials
-
Recommended materials
Book
Introduction to Bioorganic Chemistry and Chemical Biology. D. van Vranken and G. Weiss. Garland Science 2013. ISBN 978-0-8153-4214-4
Instructional formats
Lecture

Seminar

Tests
Final result
Test weight100
Minimum grade-

Assessment
Oral presentation 15%, written reports 30%

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Kies de Nederlandse taal