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Cursus: DI-408-09
DI-408-09
Drug Discovery
Cursus informatie
CursuscodeDI-408-09
Studiepunten (ECTS)7,5
Categorie / NiveauM (Master)
CursustypeCursorisch onderwijs
VoertaalEngels
Aangeboden doorFaculteit Betawetenschappen; Graduate School of Life Sciences; Graduate School of Life Sciences;
Contactpersoondr. E.E. Moret
Telefoon+316 20255134
E-maile.e.moret@uu.nl
Docenten
Docent
dr. E.E. Moret
Feedback en bereikbaarheid
Overige cursussen docent
Contactpersoon van de cursus
dr. E.E. Moret
Overige cursussen docent
Blok
1  (03-09-2018 t/m 09-11-2018)
Aanvangsblok
1
Timeslot-: Niet van toepassing
Onderwijsvorm
Voltijd
Cursusinschrijving geopendvanaf 28-05-2018 t/m 24-06-2018
Aanmeldingsprocedurestudentenbalie
Inschrijven via OSIRISNee
Inschrijven voor bijvakkersNee
VoorinschrijvingNee
WachtlijstNee
PlaatsingsprocedureStudiepunt/Student desk
Cursusdoelen
After completing the module the student is able to:
 
  • Distinguish and describe the phases of drug discovery.
  • Know how the drug discovery cycle works, where screening leads to more and more optimised lead compounds.
  • Understand and apply the techniques to find and make new active molecules.
  • Know the strengths and weaknesses of novel techniques of drug target finding and evaluation.
  • Understand what the drug will do in the body and which tests are needed before it can be used in a clinical setting.
  • Come up with ideas about drug delivery and targeting for drugs, vaccines and genes.
  • Have a profound understanding of the possibilities and restrictions of drug discovery strategies.
  • Be acquainted with the UIPS research groups.
  • Apply knowledge to an important medical problem.
  • Systematically solve problems and perform literature research.
  • Make and present a study design and a research proposal.
  • Work in an international, multidisciplinary team.
Inhoud
Description of content 
The consecutive steps of the current paradigm are discussed following the course book of H.P.Rang. We begin with the history of Drug Discovery. Then we discuss choosing the project; choosing the target, finding a lead and optimising the lead. Supporting workshops will deal with bioinformatics, computer-assisted drug discovery, quantitative pharmacology. Furthermore, students will spend almost half of their time in teams that have to present an innovative research proposal
There will be a two-day excursion to the Dutch Medicines Days.
 

Mandatory for students in Master’s programme Drug Innovation: YES.
Optional for students in other Master’s programmes GS-LS: NO

This course is open to Bachelors of Science. Applicants are familiar with: molecular biology, biochemistry, pharmacology, organic chemistry
Ingangseisen
Bronnen van zelfstudie
web.science.uu.nl/ud and
Drug Discovery and Development: Technology in Transition. 2nd edition, Edited by R.G. Hill and H.P. Rang, Churchill Livingstone 2013, ISBN 978-0-7020-4299-7
Verplicht materiaal
-
Aanbevolen materiaal
Boek
Drug Discovery and Development: Technology in Transition. 2nd edition, Edited by R.G. Hill and H. P. Rang, Churchill Livingstone 2013 ISBN 978-0-7020-4299-7
Software
UA10049 Yasara 12.11.25.W UA10298 Molecular Conceptor 2.17 SPSS
Werkvormen
Groepsonderwijs

hoorcollege

Hoorcollege 1

Toetsen
eindresultaat
Weging100
Minimum cijfer-

Beoordeling
report 30%; presentation 20%; oral exam 30%; teamwork 20%

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