(CARDIO)VASCULAR BIOLOGY
Credit load: 7,5 ECTS Course code: BMW32407
Coordinator: Dr. S.C.A. De Jager Period: 2
Examiner: Dr. S.C.A. De Jager Timeslot: AD
Email address: j.vd.velde@umcutrecht.nl Level: 3
Phone: +31 88 75 58654
Content:
Cardiovascular diseases are a major cause of death in Western society. With the increase in diabetes and obesity around the globe is expected to further increase cardiovascular disease in the world. This course provide with current in-depth knowledge on the prevalence and pathogenesis vascular disease, but also include cutting-edge science that shape the future of cardiovascular research. Topics that will be addressed include basics of cardiovascular health and disease, vascular inflammation, sex and gender in cardiovascular disease, and biomarkers for cardiovascular disease. The first part of the course will focus on knowledge acquirement which will be applied during the rest of the course that include a workshop on disease modeling in cardiovascular disease, an in-depth-assignment, patient interviews and designing and presenting a research proposal. During the course the subject matter will be dealt with in a way that triggers students to be critical academics and apply the knowledge obtained for practical application in research.
Required knowledge:
Basic knowledge of physiology and immunology is required.
Learning outcomes:
Using different teaching forms, including eModules, lectures, seminars, patient interviews, and group assignments, the student will obtain in-depht knowledge of vascular (patho)biology.
More specifically at the end of the course, the student is able to:
1. understand and describe the biological aspects and current view on (cardio)vascular disease
2. clarify the role of molecular and cellular processes in the development and progression of atherosclerosis
3. explain the development of cardiovascular diseases from preclinical and clinical disciplines and describe current and possible future therapeutic interventions.
At the end of this course the student will have improved:
Academic skills:
1. formulate a research proposal to solve a scientific cardiovascular problem;
2. analyse and present a scientific problem, together with other students in a team;
3. critically assess research paper, proposals and research methods for their use in science.
Academic attitude:
At the end of this course, the student is able to show a critical and inquisitive attitude towards the developments in research to cardiovascular diseases..
Learning activities and contact time:
The course consists of lectures, e-tutorials, group meetings and private study. To understand the pathogenesis of a syndrome, the student will formulate a hypothesis form a clinical problem and make plan for research experiments. The practical part consists of demonstrations of experiments with laboratory animals, e.g. open-heart surgery and catheter interventions. Contact time is approximately 30%.
Method(s) of testing:
There will be an individual, written examination with open questions. The final grade is a combination of the grade obtained for the written examination (60%), discussion of an article (10%) and active participation during tutorials (30%). The tutorials will partly be web based.
Required material:
ยท Course manual can be purchased at Mebiose in UMC Utrecht.
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