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Course module: BMB531818
BMB531818
Systematic Reviews and Meta-Analysis of Prognosis Studies
Course info
Course codeBMB531818
EC1.5
Course goals
At the end of the course, the student will be able to:

Explain the rationale for performing a systematic review of prognostic studies
List the key steps of a systematic review of prognostic studies
Formulate a focused review question addressing a prognostic problem
Critically appraise the evidence from primary prognostic studies using the CHARMS instrument
Formulate the difficulties of meta-analysis of prognostic research
Understand, interpret and undertake systematic review and meta-analysis of prognostic studies
Content

Period (from-till):  This course is taught several times per year, during fulltime weekdays according to the following Schedule (Face-2-Face in Period A, Online in Period B):
Education form Startdate Enddate Registration period
Face-2-Face 10-06-2024 14-06-2024 BMS_P4_A
Onilne* 06-11-2023 24-11-2023 BMS_P1_B
*Online courses are only available for Epidemiology students following a full online programme.

Contact details: Educational Office Epidemiology
E-mail: msc-epidemiology@umcutrecht.nl

Registration:
Single courses — MSc Epidemiology (msc-epidemiology.nl)

Course coordinator:
Anneke Damen

Course description:
The number of primary studies evaluating prognostic factors and models is rising. Critically summarizing and analyzing the evidence form prognostic studies in a systematic review and meta analysis, respectively,  is beneficial for health care professionals seeking the best evidence. Reviews of prognostic studies are more challenging because of more variation in questions & designs, specific sources of bias & variation, and more complex statistical models, as compared to e.g. randomized therapeutic intervention trials . Several advances regarding the design, critical appraisal and statistical analysis in systematic reviews of prognostic studies, have recently been made. In this course we discuss and practice how to define your review questions, how to critically assess the methodological quality of primary prognostic studies, and which statistical methods to use for meta-analyses of the results of primary prognostic studies. The course consists of plenary presentations, small-group discussions, and computer exercises.

Literature/study material used:
-
  
Mandatory for students in own Master’s programme:
MIght be for a specialization programme of Epidemiology & Epidemiology Postgraduate
 
Optional for students in other GSLS Master’s programme:
Yes
 
Prerequisite knowledge:
In this course, we expect participants to have a basic knowledge about the principles of prognostic research and of systematic reviews and meta-analysis. A short recap on these topics will be given during the lectures and key papers will be available on this website.
 
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