After the course the student:
- can relate (epi)genetic variations to brain diseases and traits;
- is able to analyse the gene and its neuron-specific expression;
- can determine the relation between neuronal genes (gene networks and pathways);
- has knowledge of the transcriptome and how to utilize it
- has basic knowledge of programming in bioinformatics (R, UNIX).
Period (from – till): 19 November - 30 November 2018
Please Note: this course has changed from a 1 week (1,5 ECTS) to a 2 week (3 ECTS) course.
Course coordinator: Prof.dr. Roger A.H. Adan
Prof.dr. J.P.H. Burbach
Dr. K. van Eijk
Prof dr. J. H. Veldink
Every day one lecture followed by hands-on computer practical; each day finishes with a keynote lecture.
During the course there is an assignment with a final presentation (which will be assessed) and an exam.
This course provides an overview of multiple genetic tools used by neuroscientist, including: brain atlases, analysis of proteome/interactome data, GWAS/WebQTL/Phenotype analysis; (single cell) RNAseq.
Central theme: neurological and psychiatric diseases (Autism, Eating disorders, Schizophrenia, ALS, Epilepsy and Mental Retardation).
Literature/study material used
Course Modules (all web-based)
Mandatory for students in Master’s programme
Optional for students in other GSLS Master’s programme: