Learning objectives:
- Understand and apply knowledge of biofabrication, ecompassing 3D printing techniques, biomaterial science, and tissue engineering:
- Able to describe different 3D printing techniques and biomaterials used in biofabrication, as well as different applications
- Able to process medical imaging data into printable CAD models
- Able to describe the role of (stem) cells in the development of specialised tissues and appreciate the rationale for regenerative medicine strategies
- Able to describe the cell-matrix interactions and the mechanical properties of specialised tissues
- Able to describe the interaction of implanted cells and biomaterials in living organisms
- Able to describe and distinguish different in vitro, in vivo and ex vivo research models and techniques, and determine which models/techniques are appropriate for answering a specific research/clinical question
- Able to describe techniques for the in vitro manipulation of cells and biomaterials to engineer tissues for regenerative medicine purposes or in vitro models
- Able to describe which challenges and approaches dominate the frontier research in biofabrication and/or regeneration of various tissues
- Able to discuss ethical aspects of tissue engineering
- Critically evaluate scientific literature
Function effectively in multidisciplinary, international (study) groups
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Note: this is an online course stretching over 9 weeks with a study load of approximately 10 hours per week.
Period: 9 October 2017 - 10 December 2017 and 19 February - 22 April 2018
Course coordinator: Prof. dr. ir. Jos Malda
Lecturer: Iris Otto, MSc
Course content
Biofabrication combines advanced 3D fabrication techniques with biological systems to create designed tissue constructs, which can be applied for tissue engineering, as 3D in vitro biological models or as medical therapeutic products. This ecourse aims to provide the student with the fundamental knowledge on the various aspects of biofabrication, including 3D printing techniques, biomaterials, tissue engineering, applications, translation and ethics.
The subjects being addressed:
- 3D printing history, techniques, applications
- CAD/CAM, 3D modelling, STL, G code
- Medical imaging to printing
- 3D printing techniques: additive manufacturing, robotic
dispensing, fused deposition modelling, electrospinning,
stereolithography, powder printing, metal printing
- 3D printing in the clinic: devices and implants
- Biomaterials: polymers, bioinks, tissuederived matrices
- Cells and stem cells
- Cell printing
- Applications: cartilage, liver, cardiovascular system,
organonachip, in vitro models
- Translation, benchtobedside
- Automation, implementation, regulation
- Ethics
The added value for the participants:
This course provides fundamental knowledge on biofabrication and is developed by a leading research group within the biofabrication field. Weblectures are given by experts in the fields of tissue engineering, materials sicence, mechanical engineering, medicine, biology and ethics.
Registration
The registration will be via the Study guide.
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