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Course module: BMB502717
Advanced MR Physics 1
Course info
Course codeBMB502717
ECTS Credits5
Category / LevelM (Master)
Course typeCourse
Language of instructionEnglish
Offered byFaculty of Medicine; Graduate School of Life Sciences; Medical Imaging;
Contact persondr. ir. L.W. Bartels
Telephone+31 88 7558735
Contactperson for the course
dr. ir. L.W. Bartels
Other courses by this lecturer
Teaching period
MASTER  (20/08/2018 to 17/08/2019)
Teaching period in which the course begins
Time slot-: Not in use
Study mode
Remark12 Nov 2018 - 1 Feb 2019. Apply via the study guide two weeks before the start of the course.
Course application processadministratie onderwijsinstituut
Enrolling through OSIRISNo
Enrolment open to students taking subsidiary coursesYes
Waiting listNo
Course placement processadministratie onderwijsinstituut
After completing the course the student:
  1. understands the physical origin of the NMR signal;
  2. can mathematically describe the methods used for spatial encoding of the NMR signal, for signal detection and for subsequent image reconstruction;
  3. understands and can mathematically describe the methods for creating various types of signal weighting in MRI;
  4. can mathematically derive optimal parameter settings for specific MRI applications given certain prerequisites in terms of signal-to-noise-ratio, contrasts, scan duration, etc.;
  5. knows the basic concepts of pulse sequence design for MRI techniques.
Period (from – till): 12 November 2018 - 1 Febuari 2019

Course coordinator: Dr. ir. Wilbert Bartels.
Lecturers Wilbert Bartels, UMC Utrecht/Imaging Division, lecturer
Dr. Clemens Bos, UMC Utrecht/Imaging Division, lecturer
Renée Allebrandi, MA (course registration)

Course description
This advanced  MRI course covers the physical principles of MRI and sequence design issues.
Topics that will be covered are:
  • The classical NMR mode: nucleus in a magnetic field
  • Rotating reference frame & resonance
  • Bloch equations
  • Signal detection concepts
  • Signal acquisition: FID and echo techniques
  • Multi-dimensional Fourier imaging and k-space
  • Fourier image reconstruction
  • Signal, contrast and noise
  • Basic sequence design
For the lectures (morning sessions) attendance is highly recommended; the tutorial sessions in the afternoon are mandatory: students have to prepare and present assignments.

Literature/study material used
Magnetic resonance imaging: Physical principles and sequence design. E.M. Haacke, R.W. Brown, M.R. Thompson, R. Venkatesan. John Wiley & Sons, New York, 1999 and hand-outs provided by the lecturers.
At least 2 weeks before start of the course. Register via the study guide.

Optional for students in other GSLS Master’s programme:

Prerequisite knowledge:
Basic knowledge of mathematics (differential equations, vector calculus, Fourier analysis, complex functions, electromagnetism (Faraday’s law of induction, static magnetic field calculations, electromagnetic waves)) and MRI at BSc level. Preferably also the study material on MRI provided in the Medical Imaging course Medical Image Formation.
Entry requirements
Required materials
Instructional formats




Open book prelim
Test weight100
Minimum grade5.5

Kies de Nederlandse taal