Period (from – till):
18 March 2019 - 29 March 2019
J. Koedam, PhD, UMCU, DBG, Afdeling MCR en Metabolic Diseases, lecturer, supervisor, coordinator
E. Kalkhoven, PhD, UMCU, DBG, Afdeling MCR en Metabolic Diseases, lecturer and supervisor
S. van Mil, PhD, UMCU, DBG, Afdeling MCR en Metabolic Diseases, lecturer and supervisor
Prof. B. Burgering, UMCU, Afdeling MCR en Metabolic Diseases, lecturer and supervisor
Dr. T. Dansen, UMCU, Afdeling MCR, lecturer
N. Verhoeven, PhD, UMCU, DBG, Afdeling Medische Genetica, Metabole Diagnostiek, lecturer and supervisor.
The course Metabolic Pathways approaches metabolism and endocrinology from several different angles. Lectures and tutorials in the first week discuss the molecular mechanisms involved in regulating glucose, fat and protein homeostasis. Transcriptional regulation of metabolism and oxygen metabolism will be discussed, as well as metabolic dysregulation in diseases like type 2 diabetes and cancer. Finally, the course will introduce metabolomics and other diagnostic tools for monogenetic and multifactorial metabolic diseases. Presentations by students and a written exam are part of this week. In the second week students have to develop a new research aim in a small group (3-5 students) and present this as a poster.
Literature/study material used
Recent reviews and original articles
CS&D students (max. 20) apply via website: www.csnd.nl/courses
Biology of Disease students (max. 20) and other GSLS students: apply via the study guide
The maximum number of participant is 40.
Mandatory for students in Master’s programme
CSDB: can be part of the 15 EC Theoretical Courses
BoD students: This course is one of the specific cardiovascular BoD-courses. Additional to the mandatory Kick off course, BoD students should accomplish 12 EC with specific (cardiovascular) BoD courses.
Optional for students from other GSLS Master's programmes:
Yes, but only when the maximum enrolment of 40 has not yet been reached.
A bachelor degree in Biomedical Sciences or equivalent. The student must have thorough knowledge of basic biochemistry, cell biology and physiology. Basic concepts of metabolism will be recapitulated at the beginning of the course. Students should be proficient in English, and be able to quickly grasp the main points of a research paper.