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Course module: BMB436006
Cell Organisation in Health and Disease
Course info
Course codeBMB436006
ECTS Credits1.5
Category / LevelM (Master)
Course typeCourse
Language of instructionEnglish
Offered byFaculty of Medicine; Graduate School of Life Sciences; Cancer, Stem Cells and Development Biology;
Contact personM.M. Maurice
Contactperson for the course
M.M. Maurice
Other courses by this lecturer
Teaching period
BMS_P3_A  (03/02/2020 to 17/04/2020)
Teaching period in which the course begins
Time slot-: Not in use
Study mode
Remarkdate 16-20 march 2020 Apply via Osiris Student. Max 20 students
Enrolment periodfrom 28/10/2019 up to and including 24/11/2019
Course application processadministratie onderwijsinstituut
Enrolling through OSIRISYes
Enrolment open to students taking subsidiary coursesYes
Post-registration openfrom 20/01/2020 up to and including 17/02/2020
Waiting listYes
Course placement processadministratie onderwijsinstituut
At the end of the course the student:
  1. knows the state-of-the-art strategies and techniques used in membrane traffic research;
  2. knows the possibilities offered in the field of membrane traffic research;
  3. has advanced knowledge of membrane traffic and its relationship to disease and development;
  4. can use this knowledge to read series of articles on a given subject and produce integrated view onhow the studied membrane traffic defect explains the etiology of the disease or developmental defect;
  5. is able to participate in scientific discussions;
  6. is able to analyse presentations of other scientist.
Period (from – till): 16 March 2020 - 20 March 2020.
dr. Madelon Maurice
Prof. Dr. Judith Klumperman
dr. Peter vd Sluijs
dr. Catherine Rabouille
Prof.dr. Willem Stoorvogel
Invited speaker (international)
Description of content
The purpose of this Master Class has two aspects:
-Acquire basic and advanced knowledge on membrane traffic and its relationship to disease and development.
-Use this knowledge to read a series of articles on a given subject and produce an integrated view of how the studied membrane traffic defect (due to a given mutation) explains the etiology of the disease or the developmental defect.

Course organization:
- 20 students (max) will receive training in reading and interpreting scientific literature dealing with membrane traffic in disease and development.

- First, the students get 5 introductory lectures on the relationship between different aspects of membrane traffic with diseases and development by Judith Klumperman, Peter van der Sluijs, Catherine Rabouille, Willem Stoorvogel and Madelon Maurice.
-The students are divided in 5 groups and assigned a given subject that they will prepare so at the end of this week, the students are expected to: 1) provide a concise and coherent oral presentation of research papers in a format of a journal club 20 min, including 10 min discussion combining several papers (see guidelines) given by the teachers. The presentation will have to integrate the data of these papers to make a single and cohesive story while presenting primary data (see guidelines). This is an important research exercise, so you learn to read, integrate information and write an introduction, a review, a thesis, etc.
2) After the final presentation on Friday, there will be an exam: students will be asked to answer questions about all subjects (5 in total) for 1 hour. Thus it is important that the students gather sufficient information during the presentation of fellow students. The exam also drives all participants into presenting the best you can so that others can understand.

Further remarks: The week is meant to be dedicated to this course. The students have to be together all the time, either as a small or large group. The preparation of the presentation and the research proposal has to be made together as a small group to start with. Thursday, however, is dedicated to rehearse the presentation and improve it with all fellow students of the course who do not deal with the same subject but who will critically evaluate and ask questions to improve the talks.
Grades: The grade will be based on performance during the week (interest, participation 20%), the presentation itself (with individual marks of students for presentation and discussion 40%), and the exam at the end (40%)

Literature/study material used:
varies according to assignments

You can register for this course via Osiris Student. More information about the registration procedure can be found here on the Studyguide.
Maximum of 20 students.

Mandatory for students in own Master’s programme:

Optional for students in other GSLS Master’s programme:

Prerequisite knowledge:
Bsc BMW / Biology
Entry requirements
Prerequisite knowledge
Although basic mechanisms will be integrated in the teaching, the course is best suited for students that have a basic molecular understanding of subcellular organization through textbooks such as Molecular Biology of the Cell (Alberts).
Required materials
Instructional formats
Core lecture





Test weight100
Minimum grade5.5

Kies de Nederlandse taal