Description of content
The purpose of this Master Class has two aspects:
-Acquire basic and advanced knowledge on membrane traffic and its relationship to disease and development.
-Use this knowledge to read a series of articles on a given subject and produce an integrated view of how the studied membrane traffic defect (due to a given mutation) explains the etiology of the disease or the developmental defect.
- 20 students (max) will receive training in reading and interpreting scientific literature dealing with membrane traffic in disease and development.
- First, the students get 5 introductory lectures on the relationship between different aspects of membrane traffic with diseases and development by Judith Klumperman, Peter van der Sluijs, Catherine Rabouille, Willem Stoorvogel and Madelon Maurice.
-The students are divided in 5 groups and assigned a given subject that they will prepare so at the end of this week, the students are expected to: 1) provide a concise and coherent oral presentation
of research papers in a format of a journal club 20 min, including 10 min discussion combining several papers (see guidelines) given by the teachers. The presentation will have to integrate the data of these papers to make a single and cohesive story while presenting primary data (see guidelines). This is an important research exercise, so you learn to read, integrate information and write an introduction, a review, a thesis, etc.
2) After the final presentation on Friday, there will be an exam
: students will be asked to answer questions about all subjects (5 in total) for 1 hour. Thus it is important that the students gather sufficient information during the presentation of fellow students. The exam also drives all participants into presenting the best you can so that others can understand.
The week is meant to be dedicated to this course. The students have to be together all the time, either as a small or large group. The preparation of the presentation and the research proposal has to be made together as a small group to start with. Thursday, however, is dedicated to rehearse the presentation and improve it with all fellow students of the course who do not deal with the same subject but who will critically evaluate and ask questions to improve the talks.
The grade will be based on performance during the week (interest, participation 20%), the presentation itself (with individual marks of students for presentation and discussion 40%), and the exam at the end (40%)
Literature/study material used
varies according to assignments
Mandatory for students in own Master’s programme
Optional for students in other GSLS Master’s programme
Bsc BMW / Biology