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Course module: BMB404707
BMB404707
Clinical Immunology
Course info
Course codeBMB404707
EC3
Course goals
At the end of the course, the student is able to:

Knowledge
  1. explain how disordered immunological mechanisms result in diseases or disease processes (autoimmunity, allergy and immunodeficiencies)
  2. discribe the relationschip between tumor and immune system of the host and how this knowledge can be used in the development of new therapeutical strategies
  3. explain the mechanisms of chronic inflammatory reactions
  4. explain the principles of HLA-typing and HLA-matching for organ transplantation and stem cell transplantation and describe the process of organ and stem cell transplantation
Skills
  1. present a structured, critical survey of one or more scientific articles, at the level of a junior scientist;;
Attitude
  1. demonstrate a critical and inquisitive attitude towards claims concerning animal models and immunopathogenetic concepts
  2. engage into respectful interactions/discussions with other students.
Content
Period (from – till): 11 - 22 September 2023 (BMS_P1_A)

Course coordinator: Prof. dr. Dörte Hamann

Faculty:
Dr. Kristin Denzer (registration course)
Prof. dr. Dörte Hamann (course content)
Dr. Edward Knol (course content)

Course description:
Deficiency or deregulation of the immune system can lead to a kaleidoscope of clinical features which are genetically determined or induced by infections or cancer therapy. During this course pathogenesis of diseases and novel forms of immune therapy will be discussed. 

Lectures and tutorials will focus on four main topics:

1. Immunodeficiencies
2. Chronic inflammation (Autoimmune diseases and atopy)
3. Hematological malignancies
4. HLA typing, organ and stem-cell transplantation

Literature/study material used:
Mandatory:
Immunology: A. Abbas et al. Cellular and Molecular Immunology 9th edition 2018, Elsevier, Inc.

Useful other books:
Robbinson - Pathologic Basic of Disease, Alberts - Molecular Biology of the Cell

Registration:
Automatically for students I&I, together with acceptance for programme.
Other students apply for this course via Osiris Student. More information about the registration procedure can be found here on the Studyguide.

Contact:
Prof. dr. Dörte Hamann (course content): d.wenziau@umcutrecht.nl
I&I Secretariat (registration course & Osiris): secretary.iimaster@umcutrecht.nl

Mandatory for students in own Master’s programme:
Yes

Optional for students in other GSLS Master’s programme:
Admittance only in exceptional cases for students with an internship in the field of Clinical Immunology

Prerequisite knowledge

Basic Immunology equivalent to content of BMW Infectie en Afweer.
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