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Cursus: B-MBIOCES
B-MBIOCES
BiBC Essentials
Cursus informatie
CursuscodeB-MBIOCES
Studiepunten (EC)4,5
Cursusdoelen

 

General:

  • We are going to prepare you for your internship by teaching you essential skills & knowledge
  • Community building among students.
  • Getting to know the group leaders and their research.
  • Become computational: Learn to write scripts in Unix, make pipelines using bioinformatic methods, and learn about version control.
  • Become familiar with common bioinformatic and biocomplexity methods (algorithms).
  • Learn to interpret data by modeling
  • Become a quantitative biologist

 

Learning goals

general

·         Can read and understand primary literature and critically evaluate their own understanding

·         Can understand and adapt an existing workflow to perform a systematic and reproducible bioinformatics analysis

·         Understands the FAIR principles and the issues related to handling, storage and sharing of data and code

bioinformatics

·         Understand, explain and apply the basics of dimension reduction, clustering (linkage and distances) and visualisation of high dimensional data

·         Can understand and explain the concept of supervised/unsupervised machine learning and their limitations

·         Understand and explain the concepts of cross-validation and overtraining

·         Understands and explain the basics of Hidden Markov Models and its fields of application

biocomplexity

·         Understand and explain the parameter curse and ways to avoid excessive parameter numbers

·         Understand, explain and apply model parameter fitting

·         Understand and explain the relevance of space, stochasticity and multiple scales for model behaviour

·         Understand and explain basic concepts in network theory and motifs

·         Understand and explain basic concepts of excitable media and their applicability to a broad range of biological phenomena

·         Understand the basics of numerical integration


 

Inhoud

Description of content

In this 6 weeks course the most essential trades for Bioinformatics and BioComplexity will be taught. Short lectures are alternated with hands-on computer practicals and assignments. 

Topics that will be covered are: Using the lunix command line and tools. 

Building analysis pipelines 

Introduction in the many algorithms (and tools) that are used in Bioinformatics and BioComplexity amongst which are: Unix workflows, Version Control, unsupervised learning, parameter fitting, reduction, supervised learning and spatial models

  

 

Literature/study material used

Will be provided as course materials.

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